abstract：:The bedside hemodynamic assessment of the critically ill remains challenging since blood volume, arterial-venous interaction and compliance are not measured directly. Mean circulatory filling pressure (Pmcf) is the blood pressure throughout the vascular system at zero flow. Animal studies have shown Pmcf provides info...

journal_title：Annals of intensive care

authors： Wijnberge M,Sindhunata DP,Pinsky MR,Vlaar AP,Ouweneel E,Jansen JR,Veelo DP,Geerts BF

更新日期：2018-06-20 00:00:00

abstract：BACKGROUND:In randomised controlled trials, procalcitonin (PCT)-guided antibiotic treatment has been proven to significantly reduce length of antibiotic therapy in intensive care unit (ICU) patients. However, concern was raised on low protocol adherence and high rates of overruling, and thus the value of PCT-guided tre...

journal_title：Annals of intensive care

authors： Hohn A,Balfer N,Heising B,Hertel S,Wiemer JC,Hochreiter M,Schröder S

更新日期：2018-06-04 00:00:00

abstract：BACKGROUND:Ultrafast cooling by total liquid ventilation (TLV) provides potent cardio- and neuroprotection after experimental cardiac arrest. However, this was evaluated in animals with no initial lung injury, whereas out-of-hospital cardiac arrest is frequently associated with early-onset pneumonia, which may lead to ...

journal_title：Annals of intensive care

authors： Rambaud J,Lidouren F,Sage M,Kohlhauer M,Nadeau M,Fortin-Pellerin É,Micheau P,Zilberstein L,Mongardon N,Ricard JD,Terada M,Bruneval P,Berdeaux A,Ghaleh B,Walti H,Tissier R

更新日期：2018-05-02 00:00:00

abstract：OBJECTIVES:To assess outcomes at hospital discharge and day-120 after intensive care unit (ICU) discharge among patients with solid cancer admitted to ICU and to identify characteristics associated with in-hospital and day-120 after ICU discharge mortalities. DESIGN:International, multicenter, retrospective study. SE...

journal_title：Annals of intensive care

authors： Vincent F,Soares M,Mokart D,Lemiale V,Bruneel F,Boubaya M,Gonzalez F,Cohen Y,Azoulay E,Darmon M,GrrrOH: Groupe de recherche respiratoire en réanimation en Onco-Hématologie (Group for respiratory research in intensive care in Onco-Hem

更新日期：2018-03-27 00:00:00

abstract：BACKGROUND:While the process of sepsis-induced immunosuppression is now well described in adults, very little information is available on immune functions in pediatric sepsis. The current study investigated this in children with septic shock by performing immunomonitoring, including both innate (monocyte human leukocyt...

journal_title：Annals of intensive care

authors： Remy S,Kolev-Descamps K,Gossez M,Venet F,Demaret J,Javouhey E,Monneret G

更新日期：2018-03-13 00:00:00

abstract：:The majority of resuscitated patients present with underlying cardiac disease, and out of these myocardial infarction is most common. Immediate interventional treatment is recommended and routinely requires dual antiplatelet therapy including aspirin and a P2Y12-inhibitor. Therapeutic hypothermia or target temperature...

journal_title：Annals of intensive care

authors： Prüller F,Milke OL,Bis L,Fruhwald F,Scherr D,Eller P,Pätzold S,Altmanninger-Sock S,Rainer P,Siller-Matula J,von Lewinski D

更新日期：2018-02-21 00:00:00

abstract：BACKGROUND:Assessment of maximum respiratory pressures is a common practice in intensive care because it can predict the success of weaning from ventilation. However, the reliability of measurements through an intubation catheter has not been compared with standard measurements. The aim of this study was to compare max...

journal_title：Annals of intensive care

authors： Medrinal C,Prieur G,Combret Y,Quesada AR,Bonnevie T,Gravier FE,Frenoy E,Contal O,Lamia B

更新日期：2018-01-30 00:00:00

abstract：BACKGROUND:Hypoxic hepatitis (HH) is a type of acute hepatic injury that is histologically characterized by centrilobular liver cell necrosis and that is caused by insufficient oxygen delivery to the hepatocytes. Typical for HH is the sudden and significant increase of aspartate aminotransferase (AST) in response to ca...

journal_title：Annals of intensive care

authors： Van den Broecke A,Van Coile L,Decruyenaere A,Colpaert K,Benoit D,Van Vlierberghe H,Decruyenaere J

更新日期：2018-01-30 00:00:00

abstract：BACKGROUND:Hyperglycaemia is commonplace in the adult intensive care unit (ICU), associated with increased morbidity and mortality. Effective glycaemic control (GC) can reduce morbidity and mortality, but has proven difficult. STAR is a proven, effective model-based ICU GC protocol that uniquely maintains normo-glycaem...

journal_title：Annals of intensive care

authors： Stewart KW,Chase JG,Pretty CG,Shaw GM

更新日期：2018-01-10 00:00:00

abstract：BACKGROUND:Middle East respiratory syndrome (MERS) is caused by a coronavirus (MERS-CoV) and is characterized by hypoxemic respiratory failure. The objective of this study is to compare the outcomes of MERS-CoV patients before and after the availability of extracorporeal membrane oxygenation (ECMO) as a rescue therapy ...

journal_title：Annals of intensive care

authors： Alshahrani MS,Sindi A,Alshamsi F,Al-Omari A,El Tahan M,Alahmadi B,Zein A,Khatani N,Al-Hameed F,Alamri S,Abdelzaher M,Alghamdi A,Alfousan F,Tash A,Tashkandi W,Alraddadi R,Lewis K,Badawee M,Arabi YM,Fan E,Alhazzani

更新日期：2018-01-10 00:00:00

abstract：BACKGROUND:Among intensive care unit (ICU) patients with acute respiratory distress syndrome (ARDS), apart from acute cor pulmonale (ACP), the frequency and prognostic impact of basic critical care echocardiography (BCCE) abnormalities are not well defined. METHODS:Observational study of patients with ARDS, admitted f...

journal_title：Annals of intensive care

authors： See KC,Ng J,Siow WT,Ong V,Phua J

更新日期：2017-12-19 00:00:00

abstract：BACKGROUND:Pre-evaluation of endogenous immunoglobulin levels is a potential strategy to improve the results of intravenous immunoglobulins in sepsis, but more work has to be done to identify those patients who could benefit the most from this treatment. The objective of this study was to evaluate the impact of endogen...

journal_title：Annals of intensive care

authors： Martin-Loeches I,Muriel-Bombín A,Ferrer R,Artigas A,Sole-Violan J,Lorente L,Andaluz-Ojeda D,Prina-Mello A,Herrán-Monge R,Suberviola B,Rodriguez-Fernandez A,Merino P,Loza AM,Garcia-Olivares P,Anton E,Tamayo E,Trapiello W,

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:To assess the impact of a real-time random safety tool on structure, process and outcome indicators. METHODS:Prospective study conducted over a period of 12 months in two adult patient intensive care units. Safety rounds were conducted three days a week ascertaining 37 safety measures (grouped into 10 block...

journal_title：Annals of intensive care

authors： Bodí M,Oliva I,Martín MC,Gilavert MC,Muñoz C,Olona M,Sirgo G

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Intensivists' clinical decision making pursues two main goals for patients: to decrease mortality and to improve quality of life and functional status in survivors. Patient-important outcomes are gaining wide acceptance in most fields of clinical research. We sought to systematically review how well patient-...

journal_title：Annals of intensive care

authors： Gaudry S,Messika J,Ricard JD,Guillo S,Pasquet B,Dubief E,Boukertouta T,Dreyfuss D,Tubach F

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Glucose control is an important issue in post-operative patients. The objective here was to compare two insulin infusion lines by syringe pumps to assess the impact of medical devices on glycaemic variability in surgical patients under intensive insulin therapy. This open, prospective, single-centre randomis...

journal_title：Annals of intensive care

authors： Genay S,Décaudin B,Ethgen S,Alluin A,Babol E,Labreuche J,Behal H,Vantyghem MC,Odou P,Lebuffe G

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:The value of goal-directed fluid therapy in neurosurgical patients, where brain swelling is a major concern, is unknown. The aim of our study was to evaluate the effect of an intraoperative goal-directed fluid restriction (GDFR) strategy on the postoperative outcome of high-risk patients undergoing brain sur...

journal_title：Annals of intensive care

authors： Luo J,Xue J,Liu J,Liu B,Liu L,Chen G

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:As the population ages and cancer therapies improve, there is an increased call for elderly cancer patients to be admitted to the intensive care unit (ICU). This study aimed to assess short-term survival and prognostic factors in critically ill patients with solid tumors aged ≥65 years. METHODS:We conducted...

journal_title：Annals of intensive care

authors： Auclin E,Charles-Nelson A,Abbar B,Guérot E,Oudard S,Hauw-Berlemont C,Thibault C,Monnier A,Diehl JL,Katsahian S,Fagon JY,Taieb J,Aissaoui N

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Pneumonia is one of the major complications of drowning, but the optimal empirical antibiotic treatment is not clearly defined. Multidrug-resistant (MDR) bacteria and fungi have been identified in a recent series of freshwater drowning-associated pneumonia. However, microbial data in seawater drowning are sc...

journal_title：Annals of intensive care

authors： Robert A,Danin PÉ,Quintard H,Degand N,Martis N,Doyen D,Pulcini C,Ruimy R,Ichai C,Bernardin G,Dellamonica J

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Antibiotics are frequently used in intensive care units (ICUs), and their use is associated with the emergence of bacterial resistance to antibiotics. The aim of this study was to investigate the association between the emergence of Pseudomonas aeruginosa resistance and the duration of antibiotic exposure or...

journal_title：Annals of intensive care

authors： Yusuf E,Van Herendael B,Verbrugghe W,Ieven M,Goovaerts E,Bergs K,Wouters K,Jorens PG,Goossens H

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:The use of novel sepsis biomarkers has increased in recent years. However, their prognostic value with respect to illness severity has not been explored. In this work, we examined the ability of mid-regional proadrenomedullin (MR-proADM) in predicting mortality in sepsis patients with different degrees of or...

journal_title：Annals of intensive care

authors： Andaluz-Ojeda D,Nguyen HB,Meunier-Beillard N,Cicuéndez R,Quenot JP,Calvo D,Dargent A,Zarca E,Andrés C,Nogales L,Eiros JM,Tamayo E,Gandía F,Bermejo-Martín JF,Charles PE

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:The choice of empirical antimicrobial therapy for pneumonia in intensive care unit (ICU) is a challenge, since pneumonia is often related to multidrug-resistant pathogens, particularly extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E). To prevent the overuse of broad-spectrum antimicrobial ...

journal_title：Annals of intensive care

authors： Carbonne H,Le Dorze M,Bourrel AS,Poupet H,Poyart C,Cambau E,Mira JP,Charpentier J,Amarsy R

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Optimal sedation and analgesia is a challenge in paediatric intensive care units (PICU) because of difficulties in scoring systems and specific metabolism inducing tolerance and withdrawal. Excessive sedation is associated with prolonged mechanical ventilation and hospitalisation. Adult and paediatric data s...

journal_title：Annals of intensive care

authors： Dreyfus L,Javouhey E,Denis A,Touzet S,Bordet F

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Venous thromboembolism (VTE) is one of the most common preventable causes of in-hospital death in trauma patients surviving their injuries. We assessed the prevalence, incidence and risk factors for deep venous thrombosis (DVT) and pulmonary embolism (PE) in critically ill trauma patients, in the setting of ...

journal_title：Annals of intensive care

authors： Hamada SR,Espina C,Guedj T,Buaron R,Harrois A,Figueiredo S,Duranteau J

更新日期：2017-09-12 00:00:00

abstract：BACKGROUND:Extracorporeal cardiopulmonary resuscitation (ECPR) has been considered in selected candidates with potentially reversible causes during a limited period. Candidate selection and the identification of predictable conditions are important factors in determining outcomes during CPR in the emergency department ...

journal_title：Annals of intensive care

authors： Lee SW,Han KS,Park JS,Lee JS,Kim SJ

更新日期：2017-08-30 00:00:00

abstract：BACKGROUND:Middle East respiratory syndrome coronavirus (MERS-CoV) has caused several hospital outbreaks, including a major outbreak at King Abdulaziz Medical City, a 940-bed tertiary-care hospital in Riyadh, Saudi Arabia (August-September 2015). To learn from our experience, we described the critical care response to ...

journal_title：Annals of intensive care

authors： Al-Dorzi HM,Aldawood AS,Khan R,Baharoon S,Alchin JD,Matroud AA,Al Johany SM,Balkhy HH,Arabi YM

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Aneurysmal subarachnoid hemorrhage (SAH) is a serious condition associated with high mortality rates and long-term disability. We investigated the impact of fluid balance on neurologic outcome after adjustment for possible confounders related to intensive care therapy and extra-cerebral organ failure during ...

journal_title：Annals of intensive care

authors： Sakr Y,Dünisch P,Santos C,Matthes L,Zeidan M,Reinhart K,Kalff R,Ewald C

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:The initial management of a trauma patient is a critical and demanding period. The use of extended focused assessment sonography for trauma (eFAST) has become more prevalent in trauma rooms, raising questions about the real "added value" of chest X-rays (CXRs) and pelvic X-rays (PXR), particularly in haemody...

journal_title：Annals of intensive care

authors： Hamada SR,Delhaye N,Kerever S,Harrois A,Duranteau J

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Continuous glucose monitoring (CGM) has not yet been implemented in the intensive care unit (ICU) setting. The purpose of this study was to evaluate reliability, feasibility, nurse acceptance and accuracy of the Medtronic Sentrino(®) CGM system in critically ill patients. METHODS:Sensors were inserted into ...

journal_title：Annals of intensive care

authors： Wollersheim T,Engelhardt LJ,Pachulla J,Moergeli R,Koch S,Spies C,Hiesmayr M,Weber-Carstens S

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:cRel, a subunit of NF-κB, is implicated in the inflammatory response observed in autoimmune disease. Hence, knocked-out mice for cRel had a significantly higher mortality, providing new and important functions of cRel in the physiopathology of septic shock. Whether genetic variants in the human REL gene are ...

journal_title：Annals of intensive care

authors： Toubiana J,Courtine E,Tores F,Asfar P,Daubin C,Rousseau C,Ouaaz F,Marin N,Cariou A,Chiche JD,Mira JP

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Changeovers of norepinephrine infusion pumps (CNIPs) frequently lead to haemodynamic instability. The aim of this study was to identify risk factors for haemodynamic instability associated with CNIP, independent of the method used to perform the relay. METHODS:We performed a prospective study, in a universi...

journal_title：Annals of intensive care

authors： Cour M,Bénet T,Hernu R,Simon M,Baudry T,Vanhems P,Argaud L

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Sepsis-associated acute kidney injury (SA-AKI) is an independent risk factor for death in patients with sepsis, but treatment for it is limited. To improve the diagnosis and treatment of SA-AKI, we must first understand its pathogenesis. Recently, interleukin (IL)-17A has been shown to be associated with the...

journal_title：Annals of intensive care

authors： Luo CJ,Luo F,Zhang L,Xu Y,Cai GY,Fu B,Feng Z,Sun XF,Chen XM

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Knowledge of patients' height is essential for daily practice in the intensive care unit. However, actual height measurements are unavailable on a daily routine in the ICU and measured height in the supine position and/or visual estimates may lack consistency. Clinicians do need simple and rapid methods to e...

journal_title：Annals of intensive care

authors： L'her E,Martin-Babau J,Lellouche F

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Red blood cell (RBC) transfusion has been associated with nosocomial infection in the critically ill patients. However, this association may be confounded by length of stay, as prolonged intensive care unit (ICU stay) increases both risk of infection and risk of transfusion. Also, it is not known whether spe...

journal_title：Annals of intensive care

authors： Engele LJ,Straat M,van Rooijen IHM,de Vooght KMK,Cremer OL,Schultz MJ,Bos LDJ,Juffermans NP,MARS Consortium.

更新日期：2016-12-01 00:00:00

abstract：:This review examines the available evidence for targeting a specific mean arterial pressure (MAP) in sepsis resuscitation. The clinical data suggest that targeting an MAP of 65-70 mmHg in patients with septic shock who do not have chronic hypertension is a reasonable first approximation. Whereas in patients with chron...

journal_title：Annals of intensive care

authors： Kato R,Pinsky MR

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:We performed a meta-analysis of randomized controlled trials (RCTs) to determine if daily bathing with chlorhexidine decreased hospital-acquired BSIs in critically ill patients. METHODS:We searched the MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials databases to identify randomized contr...

journal_title：Annals of intensive care

authors： Choi EY,Park DA,Kim HJ,Park J

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Sepsis is a common condition that has a high mortality and morbidity that need prompt diagnosis and treatment. Biomarkers like Soluble CD14 subtype (sCD14-ST, presepsin) may be useful in identifying patients with sepsis and its diagnostic superiority has been confirmed by several preliminary studies. The aim...

journal_title：Annals of intensive care

authors： Zheng Z,Jiang L,Ye L,Gao Y,Tang L,Zhang M

更新日期：2015-12-01 00:00:00

abstract：:Jean-Luc Diehl The French Intensive Care Society organized on 5th and 6th June 2014 its 4th "Paris International Conference in Intensive Care", whose principle is to bring together the best international experts on a hot topic in critical care medicine. The 2014 theme was "Breakthrough in cardiac arrest", with many hi...

journal_title：Annals of intensive care

authors： Kudenchuk PJ,Sandroni C,Drinhaus HR,Böttiger BW,Cariou A,Sunde K,Dworschak M,Taccone FS,Deye N,Friberg H,Laureys S,Ledoux D,Oddo M,Legriel S,Hantson P,Diehl JL,Laterre PF

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Patients in the intensive care unit (ICU) are more prone to drug-drug interactions (DDIs). The software and charts that indicate all interactions may not be proper for clinical usage. This study aimed to identify the main drug classes associated with clinically significant DDIs in cardiothoracic ICU and cate...

journal_title：Annals of intensive care

authors： Baniasadi S,Farzanegan B,Alehashem M

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Healthcare-associated bloodstream infections are related to both increased antibiotic use and risk of adverse outcomes. An in-depth understanding of their epidemiology is essential to reduce occurrence and to improve outcomes by targeted prevention strategies. The objectives of the study were to determine th...

journal_title：Annals of intensive care

authors： Culshaw N,Glover G,Whiteley C,Rowland K,Wyncoll D,Jones A,Shankar-Hari M

更新日期：2014-11-25 00:00:00

abstract：:The death of a loved one is often an ordeal and a tragedy for those who witness it, as death is not merely the end of a life, but also the end of an existence, the loss of a unique individual who is special and irreplaceable. In some situations, end-of-life signs, such as agonal gasps, can be an almost unbearable "sig...

journal_title：Annals of intensive care

authors： Daubin C,Haddad L,Folscheid D,Boyer A,Chalumeau-Lemoine L,Guisset O,Hubert P,Pillot J,Robert R,Dreyfuss D

更新日期：2014-07-08 00:00:00